On Friday, the 49ers announced that six of the seven players who were ineligible to play in the regular season finale versus the Rams had their names exposed. Plus, the 49ers' Brock Purdy, who is likely to wear the uniform of the team's emergency third quarterback, will be the seventh.
On Sunday, Purdy—who threw for 4,280 yards this season, setting a new club record—would only play if injuries sidelined starter Sam Darnold and backup Brandon Allen.
Head coach Kyle Shanahan announced that six players would not be participating in Week 18's game due to injury: Christian McCaffrey (calf), Arik Armstead (foot, knee), Ross Dwelley (ankle), Ambry Thomas (hand), and starting safeties Ji'Ayir Brown (knee) and Tashaun Gipson (quadriceps).
Wide receiver Jauan Jennings is considered doubtful since he has been out for the last two games while the 49ers were in the NFL's concussion protocol.
After placing receiver Ray-Ray McCloud on injured reserve, Shanahan said that the 49ers will activate him. To include him on the 53-man roster, the club will need to make an identical move. Two players from San Francisco's practice squad are anticipated to be activated so they may play a key role in the game against the Rams.
As the regular season comes to a close, the 49ers own a 12-4 record and have already secured the No. 1 seed in the NFC. Due to roster restrictions, they are unable to sit all of their players who are considered to be Pro Bowl level.
As long as eight offensive linemen are active, each team can wear a maximum of 48 players. The 49ers general manager, John Lynch, stated on Friday morning during his weekly interview on KNBR that Pro Bowl left tackle Trent Williams is anticipated to play.
Because of their first-round bye, the 49ers will get to play their playoff games on home turf. This next Saturday, January 20, Levi's Stadium will most likely host their inaugural playoff game. Before Sunday's game against the Rams, the 49ers have the following injury report: